Biological Sciences

Office: 1360 Biological Sciences; 313-577-2873
Chairperson: David L. Njus
Associate Chairperson: Edward M. Golenberg
http://clas.wayne.edu/biology


 

ALCEDO, JOY A.: Ph.D., University of Zurich; M.S., Dartmouth University; B.A., College of Saint Rose; Associate Professor

ANSARI, ATHAR: Ph.D., M.Sc., B.Sc., University of Delhi; Associate Professor

ARKING, ROBERT: Ph.D., Temple University; B.S., Dickinson College; Professor

BENINGO, KAREN A.: Ph.D., University of Michigan; B.Sc., Michigan State University; Associate Professor

CROZIER, MARTIN: Ph.D., University of Windsor; Lecturer

CUNNINGHAM, PHILIP R.: Ph.D., Southern Illinois University; B.A., Murray State University; Associate Professor

DOWLING, THOMAS E.: Ph.D., Wayne State University; B.S., University of Michigan; Professor

FAN, CHUANZHU: Ph.D., North Carolina State University; M.S., Chinese Academy of Agricultural Sciences; B.S., Northeast Normal University; Associate Professor

FREEMAN, D. CARL: Ph.D., M.S., Brigham Young University; B.S., University of Utah; Professor Emeritus

FRIEDRICH, MARKUS: Ph.D., B.S., Ludwig-Maximilians-Universitaet; Professor

GANGWERE, STANLEY K.: Ph.D., M.S., B.A., University of Michigan; Professor Emeritus

GOLENBERG, EDWARD M.: Ph.D., State University of New York at Stony Brook; B.A., Johns Hopkins University; Professor

GREENBERG, MIRIAM L.: Ph.D., Albert Einstein College of Medicine; M.S., Loyola University; B.A., Reed College; Professor

GU, HAIDONG: Ph.D., Ohio State University; M.S., Chinese Academy of Medical Sciences; B.S., Fudan University; Associate Professor

HAO, WEILONG: Ph.D., McMaster University; M.S., B.S., Nankai University; Assistant Professor

HARI, V.: Ph.D., M.S., University of Madras; B.S., Annamalai University; Associate Professor Emeritus

HEBERLEIN, GARRETT: Ph.D., M.S., Northwestern University; B.A., Ohio Wesleyan University; Professor Emeritus

HIGGS, PENELOPE I.: Ph.D., B.S., Washington State University; Assistant Professor

HOOD, GLEN: Ph.D., University of Notre Dame; M.S., Texas State Universty; B.S., Texas State University; Assistant Professor (Research)

KASHIAN, DANIEL M.: Ph.D., University of Wisconsin, Madison; M.S., B.S., University of Michigan; Professor and Associate Chair

KASHIAN, DONNA R.: Ph.D., University of Wisconsin; M.S., Michigan State University; B.S., Eastern Michigan University; Associate Professor

KENNEY, JUSTIN: Ph.D., Temple University; B.S., B.A., Case Western Reserve University; Assistant Professor

MELLER, VICTORIA H.: Ph.D., University of North Carolina-Chapel Hill; B.S., Cornell University; Professor and Chair

MIZUKAMI, HIROSHI: Ph.D., University of Illinois; B.A., International Christian University of Tokyo; Professor Emeritus

MOORE, WILLIAM S.: Ph.D., University of Connecticut; B.S., Michigan State University; Professor Emeritus

MYHR, KAREN L.: Ph.D., B.S., University of Michigan; Assistant Professor (Research)

NJUS, DAVID L.: Ph.D., Harvard University; B.S., Massachusetts Institute of Technology; Professor

PILE, LORI A.: Ph.D., University of Cincinnati; B.Sc., University of Toledo; Associate Professor

POPADIC, ALEKSANDAR: Ph.D., University of Georgia; B.S., University of Belgrade; Associate Professor

SADAGURSKI, MARIANNA: Ph.D., B.Sc., Tel Aviv University; Assistant Professor

SCHRADER, JARED: Ph.D., Northwestern University; B.S., Colorado State University; Assistant Professor

SODJA, ANN: Ph.D., University of California; M.S., Ohio State University; A.B., Ursuline College; Associate Professor

STEINER, CHRISTOPHER: Ph.D., Michigan State University; B.S. University of California-Los Angeles; Associate Professor

THOMAS, ROBERT A.: Ph.D., M.S., Wayne State University; B.S., City University of New York; Lecturer

TUCKER, JAMES D.: Ph.D., Oregon Health Sciences University; B.S., University of California-Davis; Professor Emeritus

TURCHYN, NATALIYA: Ph.D., B.S., Wayne State University; Senior Lecturer

VANBERKUM, MARK: Ph.D., Baylor College of Medicine; M.Sc., B.Sc., University of Toronto; Professor

BIO 5020 Comprehensive Virology Cr. 3

Course provides students with a comprehensive knowledge of molecular virology, from viral classification, vital structures and life cycles, to host response and global health. Offered for undergraduate credit only. Offered Fall.

Prerequisites: BIO 2200 with a minimum grade of C-, BIO 2600 with a minimum grade of C-, and BIO 3070 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

BIO 5040 Biometry Cr. 4

Quantitative methods in biology. Statistical approach to data analysis and the design of experiments. Laboratory section permits actual analysis of selected statistical problems. Offered Intermittently.

Prerequisites: (BIO 3070 with a minimum grade of C- or BIO 4130 with a minimum grade of C-) and MAT 1800-6XXX with a minimum grade of C-

Course Material Fees: $15

BIO 5060 Special Topics Cr. 1-6

Formalized treatment of the current state of knowledge in a significant area of biology. Topics to be announced in Schedule of Classes. Offered Intermittently.

Prerequisites: BIO 2600 with a minimum grade of C-

Repeatable for 6 Credits

BIO 5080 Cellular Basis of Animal Behavior Cr. 3

Relationship between behavior and neuroscience using a variety of animal models, each examined from the level of natural behavior progressively to the cellular level. Topics include: sensory systems, motor behavior, and learning. Offered Winter.

Prerequisites: BIO 2600 with a minimum grade of C-

Equivalent: PSY 5080

BIO 5100 Aquatic Ecology Cr. 4

Physical, chemical and biological processes occurring in lakes, streams and wetlands. Offered for undergraduate credit only. Offered Every Other Year.

Prerequisites: BIO 1500 with a minimum grade of C- and BIO 3500 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

Course Material Fees: $67

BIO 5150 Genomics Cr. 3

Introduction to the theory and practice of genomics. Topics include sequencing and mapping, overview of genomes, comparative genomics, transcriptomes, population genetics and genomics, basic bioinformatics and statistics, population-level variation (SNPs, MNPs, indels), ethics, evolutionary genomics, and functional genomics. Offered for undergraduate credit only. Offered Fall.

Prerequisites: BIO 3070 with a minimum grade of C- and BIO 3100 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

BIO 5180 Field Investigations in Biological Sciences Cr. 12

Field studies of one to fifteen weeks, emphasizing biological principles and techniques demonstrated in the field. Offered Intermittently.

Prerequisites: (BIO 2200 with a minimum grade of C- or BIO 2600 with a minimum grade of C-), BIO 1500 with a minimum grade of C-, and BIO 1510 with a minimum grade of C-

Course Material Fees: $10

Repeatable for 20 Credits

BIO 5240 Molecular Systems Biology Cr. 3

Introduces the basic design principles of biological circuits and networks and their functional designs at the molecular, pathway, whole cell, and population levels. Students will perform a comprehensive group project to build a computational model of a simple biological network. Offered Every Other Year.

Prerequisites: BIO 3070 and PHY 2140

BIO 5280 Bioinformatics Cr. 3

Basic Linux commands and PERL programming skills, sequence comparison, phylogenetic analysis, gene/genome patterns. Offered for undergraduate credit only. Offered Winter.

Prerequisites: BIO 3070 with a minimum grade of C- and BIO 3100 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

BIO 5290 Evolutionary Medicine Cr. 3

Examines the recent trend in applying fundamental evolutionary concepts to medical field and how this trend can lead to better treatment and therapy development. Students will explore a range of topics, from what is a disease to body defenses and reproductive medicine, by reading and discussing assigned material from their textbooks and selected research articles. Offered Winter.

Prerequisite: BIO 3070 with a minimum grade of C-

BIO 5310 Infections and Innate Immunity Cr. 3

There is a constant arms race between pathogens and their hosts. The hosts equip multiple lines of defense to prevent the invading pathogens, and the pathogens uses a wide variety of arsenals to counteract host defense. This course is designed to introduce the infection strategies used by bacterial pathogens and the anti-microbial responses in the host cells at cellular and molecular levels. The course will cover small molecules, post-translational modifications, protein interactions, and molecular machineries that are involved in the host-pathogen interactions. Offered Fall.

Prerequisite: BIO 2200 with a minimum grade of C- and BIO 2600 with a minimum grade of C-

BIO 5330 Principles and Applications of Biotechnology I Cr. 3

Review of origins of molecular biotechnology and its characteristic technologies; survey of applications of biotechnology to problems in industries. Offered Fall.

Prerequisites: BIO 2200 with a minimum grade of C-, BIO 3070 with a minimum grade of C-, and BIO 3100 with a minimum grade of C-

BIO 5440 Terrestrial Ecology Cr. 4

Ecology of forests and grasslands. Field study and interpretation of ecological processes. Importance of species-site relationships and disturbance history. Offered for undergraduate credit only. Offered Every Other Year.

Prerequisites: BIO 1500 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

Course Material Fees: $110

BIO 5490 Population and Community Ecology Cr. 3

Population dynamics of animals and plants. Life history theory. Species interactions. Structure and dynamics of communities. Offered for undergraduate credit only. Offered Every Other Year.

Prerequisites: BIO 1500 with a minimum grade of C- and BIO 4130 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

BIO 5540 Landscape Ecology Cr. 3

Concepts, methods, and applications of landscape ecology; causes and implications of ecological patterns and heterogeneity on landscapes; interrelationships of patterns and ecological processes. Offered Every Other Year.

Prerequisites: BIO 1500 with a minimum grade of C- and BIO 3500 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

BIO 5610 Developmental Biology Lab Cr. 1

Slides, models, and 4-D computer programs used to enable the student to know and recognize the cascade of structural changes that take place during the embryological developmental pathways. Offered Winter.

Prerequisites: BIO 5620 with a minimum grade of C- (may be taken concurrently)

Course Material Fees: $55

BIO 5620 Developmental Biology Cr. 3

An analytical and comparative study of genetic and cellular mechanisms and their interaction with environmental factors to effect the developmental mechanisms which produce the adult organism. Origin and unfolding of structural patterns characteristic of different species; their evolutionary origins. Offered Winter.

Prerequisites: BIO 3070 with a minimum grade of C-

BIO 5640 Cancer Biology Cr. 3

Introduction to integrated analysis of cancer and cell biology, pathology, etiology and therapy. Offered Intermittently.

Prerequisites: BIO 2600 with a minimum grade of C-, BIO 3070 with a minimum grade of C-, and BIO 3100 with a minimum grade of C-

BIO 5660 Neural Signaling in Health and Disease Cr. 3

Addresses major principles of how various brain systems regulate physiological processes of the body function, both individually and as an integrated unit. Includes principles of physiological communication as it relates to homeostasis, metabolism, and both neural and endocrine communication; emphasis is given not only to major principles but also to how these principles were developed. Topics include (but are not limited to) dysfunction and disorders of the central nervous system (CNS) in the context of signaling pathways and hormonal systems, neurodegeneration, interaction between neurons and glia cells and neuroinflammation. Offered Fall.

Prerequisite: BIO 3200 with a minimum grade of C-

BIO 5680 Basic Endocrinology Cr. 3

Basic description of the human endocrine system, the endocrine control of several physiologic processes (growth, development, metabolism and reproduction), and a description of common endocrine disorders. Offered Fall.

Prerequisites: BIO 3200 with a minimum grade of C- or BIO 4120 with a minimum grade of C-

Equivalent: PSL 5680

BIO 5750 Biology of Longevity and Aging Cr. 3

Longevity, aging and senescence viewed as fundamental biological processes common to most organisms. Data-based discussion of investigative methods and accepted facts regarding the mechanisms underlying longevity and aging, coupled with critical discussion of behavioral and biological interventions known to retard or reverse the aging processes. Systems biology overview of the process, including societal parameters necessary to the maintenance of longevity. Offered for undergraduate credit only. Offered Winter.

Prerequisites: BIO 3070 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

BIO 5890 Neuroplasticity Cr. 3

Neuroplasticity is the study of the ways the brain changes in response to genetic controls, and to the internal and external environments. Neuroplasticity includes neural development (neurogenesis and migration, neural differentiation, axon pathway formation, and synapse formation and maturation), mechanisms of learning and memory, homeostasis of excitability, aging, diseases, and responses to injury. To explore these topics, students will read and discuss readings from their textbook and seminal research articles from a variety of animal models, and run simulations. Offered Winter.

Prerequisite: BIO 4690 with a minimum grade of C-

BIO 5996 Senior Research Cr. 1-2

Original research. To be taken under direction of Biological Sciences faculty. Offered for undergraduate credit only. Offered Every Term.

Restriction(s): Enrollment limited to students with a class of Senior; enrollment is limited to Undergraduate level students.

Repeatable for 3 Credits

BIO 6000 Molecular Cell Biology I Cr. 3

Analysis of cell structure at the molecular and cellular levels and the physiological consequences of these structures: isolation, physico-chemical properties, and biological attributes of cells, organelles, and biopolymers including nucleic acids, proteins, and lipids. Offered Fall.

Prerequisite: BIO 2600 (may be taken concurrently) with a minimum grade of C and BIO 3100 (may be taken concurrently) with a minimum grade of C

BIO 6010 Molecular Cell Biology II Cr. 3

Analysis of cell regulation at the molecular level. Cell development and differentiation. Genetic mechanisms including: DNA synthesis and repair, mechanism of gene expression and control. Offered Winter.

Prerequisite: BIO 6000 with a minimum grade of C-

BIO 6020 Methods of Analyses Cr. 4

Design and execution of experiments in molecular biology. Topics include: laboratory safety, scientific documentation, database searching, development of experimental protocols, error analysis, solutions and buffers, electrophoretic separation of proteins and nucleic acids, basic immunohistochemistry, bioimaging, and scientific ethics. Offered Fall.

Prerequisites: BIO 4110 with a minimum grade of C- (may be taken concurrently) (must be taken at WSU) or BIO 5330 with a minimum grade of C- (may be taken concurrently) (must be taken at WSU)

Course Material Fees: $50

BIO 6055 Biology of the Eye Cr. 3

Introduction to biology of eye structure/function, and to causes and clinical treatments of eye-related disorders and diseases. Offered for undergraduate credit only. Offered Fall.

Prerequisite: BIO 2600 with a minimum grade of C- and BIO 3100 with a minimum grade of C-

Restriction(s): Enrollment is limited to Undergraduate level students.

Course Material Fees: $25

Equivalent: ANA 6050, PYC 6050

BIO 6060 Molecular Evolution Cr. 3

Patterns and processes of evolutionary change on the DNA sequence level. Emphasis on models of nucleotide substitutions, and genic evolution. Methods of phylogenetic inference. Offered Intermittently.

Prerequisite: BIO 3070 with a minimum grade of C- and (BIO 4200 (may be taken concurrently) with a minimum grade of C-

BIO 6090 Population Genetics Cr. 3

Theoretical bases for microevolutionary change in natural populations of organisms; basic to study of evolutionary genetics and evolutionary ecology. Offered Intermittently.

Prerequisite: BIO 3070 with a minimum grade of C-

BIO 6120 Molecular Biology Laboratory I Cr. 3

Laboratory exercises illustrate methods and concepts of molecular biology and recombinant DNA analysis. Offered Winter.

Course Material Fees: $30

BIO 6160 Proteins and Proteomics Cr. 3

Structure and dynamics of proteins at the molecular level. Strategies used to biochemically purify, analyze, and characterize proteins. Offered Winter.

Prerequisite: BIO 3100 with a minimum grade of C- or CHM 5600 with a minimum grade of C- or CHM 6620 with a minimum grade of C-

BIO 6180 Membrane Biology Cr. 3

Comprehensive analysis of cellular and model membranes integrating molecular structure and physiological properties. Structural, dynamic, and physiological properties examined, including molecular and macromolecular assemblies, physical and chemical analysis of molecular motion, functional aspects including trans-membrane signaling. Offered Intermittently.

Prerequisite: BIO 6000 with a minimum grade of C

Restriction(s): Enrollment is limited to Undergraduate level students.

BIO 6190 Advanced Special Topics Cr. 6

Formalized treatment of current state of knowledge in a significant area of biology. Topics to be announced in Schedule of Classes. Offered Intermittently.

Repeatable for 6 Credits

BIO 6330 Principles and Applications of Biotechnology II Cr. 3

Application of molecular biology and recombinant DNA technology of contemporary eukaryotic systems. Topics include: specialized application of PCR for cloning, generation of antibodies, the expression of recombinant proteins in cultured cells and transgenic animal models. Offered Winter.

Prerequisite: BIO 5330 with a minimum grade of C-

BIO 6420 Ecotoxicology and Risk Assessment Cr. 3

Provides students with an overview of ecological and environmental aspects of toxicology and pollution biology. The course will emphasize population, community, and ecosystem responses to contaminants. General understanding of ecology, chemistry, and basic statistics is essential. Offered Every Other Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 6510 Molecular Interactions Cr. 1

Introduces to methods to study biomolecular interactions. Topics covered will include yeast two-hybrid, protein tagging, protein chips, DNA/RNA footprinting, DNase,MNase, hypersensitivity, ATAC-seq, ChIP-PCR, ChIP-chip, ChIP-seq, HITS-CLIP, PAR-CLIP, three hybrid, Co-immunoprecipitation, EMSA, flourescence polarization and FRET, SPR, isothermal calorimtery and microscale thermophoresis, proximity labeling and lipid: protein interactions. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 6520 Gene Expression Manipulation Systems Cr. 1

Introduces methods to manipulate gene expression. Topics include: Bacterial transformation methods - natural vs artificial competency, conjugation, phage transduction. Eukaryotic cell culture transfection methods - transient and stable. Transgenic organism manipulation: methods for gene knock-out and inducible expression including - homologous recombination, site specific recombination, Lambda red recombination, markerless in-frame deletion, Cre-Lox, transposons, RNAi, CRISPR, TALENS, P-element mutagenesis, inducible/repressible promoters, expression reporters. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 6530 Protein Structure and Dynamics Cr. 1

Provides a solid understanding of the structure of proteins, their physiological functions, and an understanding that the molecular basis of a number of diseases is associated with protein abnormalities. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 6540 Principles of Genetic Analysis Cr. 1

Emphasizes the theory and applications of modern genetic methods of analysis. Practical and theoretical aspects of methods will be considered. Exams and quizzes will focus on concepts, experimental design and strategy. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 6690 Special Topics in Neurobiology Cr. 3

This course will enable students to apply their knowledge of neurobiology to explore a current research area in depth. The course will involve reading and discussing articles from the scientific literature. Offered Winter.

Prerequisites: BIO 4690 with a minimum grade of C-

BIO 6700 Responsible Conduct of Research Cr. 1

Fulfills federal requirements for in person faculty-led training in scientific ethics and responsible conduct of research. Offered Fall.

BIO 6890 Introduction to Research Practice - Honors Cr. 1

Provides instruction in basic laboratory safety and accepted standards for research conduct. It will provide professional development and networking opportunities for students interested in careers in research and the biomedical sciences. Instruction may be provided in the form of reading assignments, discussions, lectures and case studies. It is a co-requisite for students enrolling in BIO 6891-6894 for the first time. Offered Every Term.

Prerequisites: BIO 6891-6894 with a minimum grade of C- (may be taken concurrently)

BIO 6891 Honors Undergraduate Research in Biological Sciences Cr. 1

Original research performed under the guidance of a faculty member. Registration is by permission only. Offered Every Term.

Prerequisites: BIO 6890 with a minimum grade of C- (may be taken concurrently)

BIO 6892 Honors Undergraduate Research in Biological Sciences Cr. 2

Original research performed under the guidance of a faculty member. Registration is by permission only. Offered Every Term.

Prerequisites: BIO 6890 with a minimum grade of C- (may be taken concurrently)

BIO 6893 Honors Undergraduate Research in Biological Sciences Cr. 3

Original research performed under the guidance of a faculty member. Registration is by permission only. Offered Every Term.

Prerequisites: BIO 6890 with a minimum grade of C- (may be taken concurrently)

BIO 6894 Honors Undergraduate Research in Biological Sciences Cr. 4

Original research performed under the guidance of a faculty member. Registration is by permission only. Offered Every Term.

Prerequisites: BIO 6890 with a minimum grade of C- (may be taken concurrently)

BIO 6990 Honors Directed Study in Biology Cr. 1-4

To be taken under direction of Biological Sciences faculty. Offered for undergraduate credit only Offered Every Term.

Restriction(s): Enrollment is limited to students with a major in Biological Sciences Honors or Biological Sciences; enrollment is limited to Undergraduate level students; enrollment limited to students in a BS in Biological Science or Bachelor of Arts degrees.

Repeatable for 99 Credits

BIO 6994 Technical Communication in Molecular Biotechnology Cr. 3

Methods of written and oral communication in the biotechnology field. Offered Winter.

BIO 6999 Honors Undergraduate Research Thesis Cr. 2

Preparation of a thesis, satisfactory completion of which assures Honors graduation, providing performance in preceding Honors courses has been at Honors level; to be taken under direction of Biological Sciences faculty. Offered for undergraduate credit only. Offered Every Term.

Prerequisite: BIO 6891 with a minimum grade of C- or BIO 6892 with a minimum grade of C- or BIO 6893 with a minimum grade of C- or BIO 6894 with a minimum grade of C- or BIO 6990 with a minimum grade of C-

Restriction(s): Enrollment is limited to students with a major in Biological Sciences Honors; enrollment is limited to Undergraduate level students.

BIO 7000 Recent Advances in Cellular and Developmental Biology Cr. 3

Formalized and in-depth treatment of the current state of knowledge in a significant area of cell and molecular biology. Topics to be announced in Schedule of Classes . Offered Intermittently.

Restriction(s): Enrollment is limited to Graduate level students.

Repeatable for 6 Credits

BIO 7011 Principles of Toxicology Cr. 3

Basic concepts and principles of toxicology, including toxicity of major classes of chemicals (pesticides, solvents, metals) and organ systems (renal, immune, digestive, neuro and respiratory) affected. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

Equivalent: PHC 7410

BIO 7020 Comprehensive Virology Cr. 3

Course provides students with a comprehensive knowledge of molecular virology, from viral classification, vital structures and life cycles, to host response and global health. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7040 Signaling Transduction Mechanisms Cr. 3

Overview of signaling strategies and mechanisms used by prokaryotes and eukaryotes (including plants) to sense and respond to extracellular or intracellular stimuli. Additional study of bioinformatic, biochemical, and genetics approaches to characterization of signaling proteins, systems and networks. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7045 Biometry Cr. 4

Provides practical tools for the design of experiments, data exploration and statistical analysis of data. Prepares students to begin to design scientific studies and experiments, critically evaluate data and test hypotheses via data analysis. While the course will delve into some underlying statistical theory, a major emphasis will be providing exposure to and hands-on experience with basic approaches to the analysis of univariate and multivariate data. Offered Yearly.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7055 Biology of the Eye Cr. 3

Integrated introduction to basic biological structure/function of the eye; causes and clinical treatments of eye-related disorders and diseases. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

Equivalent: ANA 7055

BIO 7060 Evolutionary and Developmental Biology Cr. 3

Introduction to animal diversity. Genetic pathways and networks in development; focus on limb and organ formation. Evolving developmental pathways: case studies. Genetic source materials for developmental evolution. Speciation and developmental evolution. Offered Every Other Year.

Prerequisite: BIO 5620 with a minimum grade of C-

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7090 Molecular Genetics of Development Cr. 3

An examination of the current and classical research literature dealing with the role of gene action in development. Offered Intermittently.

Prerequisite: BIO 5620 with a minimum grade of C-

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7110 Aquatic Ecology Cr. 4

Physical, chemical and biological processes occurring in lakes, streams, and wetlands. Offered Every Other Fall.

Restriction(s): Enrollment is limited to Graduate level students.

Course Material Fees: $67

BIO 7150 Genomics Cr. 3

Introduction to the theory and practice of genomics. Topics include sequencing and mapping, overview of genomes, comparative genomics, transcriptomes, population genetics and genomics, basic bioinformatics and statistics, population-level variation (SNPs, MNPs, indels), ethics, evolutionary genomics, and functional genomics. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7180 Membrane Biology Cr. 3

Comprehensive analysis of cellular and model membranes integrating molecular structure and physiological properties. Structural, dynamic, and physiological properties examined, including molecular and macromolecular assemblies, physical and chemical analysis of molecular motion, functional aspects including trans-membrane signaling. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7240 Molecular Systems Biology Cr. 3

Introduces the basic design principles of biological circuits and networks and their functional designs at the molecular, pathway, whole cell, and population levels. Students will perform a comprehensive group project to build a computational model of a simple biological network. Offered Every Other Year.

Prerequisites: BIO 3070 and PHY 2140

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7280 Bioinformatics Cr. 3

Basic Linux commands and PERL programming skills, sequence comparison, phylogenetic analysis, gene/genome patterns. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7300 Communication of Research Cr. 2

During this course, students will learn to present scientific results and make compelling scientific arguments orally, visually and in written form. In addition, students will learn to professionally and constructively critique the work of others. Students will also prepare a professional resume/CV and cover letter for job applications. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7310 Sustainability of Urban Environmental Systems Cr. 2

Students will be introduced to topics in urban sustainability from multiple disciplinary perspectives such as: ecology, anthropology, communication, engineering, economics and urban planning. Questions in fostering a more sustainable urbanism will be introduced and evaluated. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

Equivalent: CE 7311

BIO 7440 Terrestrial Ecology Cr. 4

Ecology of forests and grasslands. Field study and interpretation of ecological processes. Importance of species-site relationships and disturbance history. Offered Every Other Year.

Prerequisite: BIO 1500 with a minimum grade of C- and BIO 4130 with a minimum grade of C-

Restriction(s): Enrollment is limited to Graduate level students.

Course Material Fees: $110

BIO 7490 Population and Community Ecology Cr. 3

Population dynamics of animals and plants. Life history theory. Species interactions. Structure and dynamics of communities. Offered Every Other Year.

Prerequisite: BIO 1500 with a minimum grade of C- and BIO 4130 with a minimum grade of C-

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7510 Eukaryotic Gene Structure and Function Cr. 4

Knowledge of current molecular technology is absolute prerequisite for this course; prerequisite course must have been satisfied. Analysis of structure, replication, expression and regulation of eukaryotic genome. Experimental approaches to study eukaryotic gene expression, critical comprehension of current research, design of experiments in gene expression. Offered Every Other Year.

Prerequisite: BIO 6330 with a minimum grade of C- or BIO 7780 with a minimum grade of C

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7520 Nucleic Acid Laboratory Cr. 2

The objective of the course is to provide students an in-depth understanding of nucleic acid related techniques, and their practical application in a research lab. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7530 Proteins Laboratory Cr. 2

The objective of the course is to provide students an in-depth understanding of protein purification and related techniques, and their practical application in a research lab with emphasis on: Cell lysis procedures, selection of buffer ingredients for purification, an understanding of different chromatographic procedures, and the analysis of proteins by different type of electrophoretic procedures and Western blot. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7540 Landscape Ecology Cr. 3

Concepts, methods, and applications of landscape ecology. Causes and implications of ecological patterns and heterogeneity on landscapes. Interrelationships of patterns and ecological processes. Offered Every Other Year.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7560 Light Microscopy and Imaging Cr. 2

The objective of the course is to provide students an in-depth understanding of current microscopy and imaging technology. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7610 Infections and Innate Immunity Cr. 3

There is a constant arms race between pathogens and their hosts. The hosts equip multiple lines of defense to prevent the invading pathogens, and the pathogens uses a wide variety of arsenals to counteract host defense. This course is designed to introduce the infection strategies used by bacterial pathogens and the anti-microbial responses in the host cells at cellular and molecular levels. Topics include: small molecules, post-translational modifications, protein interactions, and molecular machineries that are involved in the host-pathogen interactions. Offered Intermittently.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7660 Neural Signaling in Health and Disease Cr. 3

Addresses major principles of how various brain systems regulate physiological processes of the body function, both individually and as an integrated unit. Includes principles of physiological communication as it relates to homeostasis, metabolism, and both neural and endocrine communication; emphasis is given not only to major principles but also to how these principles were developed. Topics include (but are not limited to) dysfunction and disorders of the central nervous system (CNS) in the context of signaling pathways and hormonal systems, neurodegeneration, interaction between neurons and glia cells and neuroinflammation. Offered Fall.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7750 Biology of Longevity Aging Cr. 3

Longevity, aging and senescence viewed as fundamental biological processes common to most organisms. Data-based discussion of investigative methods and accepted facts regarding the mechanisms underlying longevity and aging, coupled with critical discussion of behavioral and biological interventions known to retard or reverse the aging processes. Systems biology overview of the process, including societal parameters necessary to the maintenance of longevity. Offered for graduate credit only. Offered Winter.

Prerequisite: BIO 3070 with a minimum grade of C-

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7890 Neuroplasticity Cr. 3

Neuroplasticity is the study of the ways the brain changes in response to genetic controls, and to the internal and external environments. Neuroplasticity includes neural development (neurogenesis and migration, neural differentiation, axon pathway formation, and synapse formation and maturation), mechanisms of learning and memory, homeostasis of excitability, aging, diseases, and responses to injury. To explore these topics, students will read and discuss readings from their textbook and seminal research articles from a variety of animal models, and run simulations. No credit after BIO 5890. Offered Winter.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 7996 Research Problems Cr. 1-8

Original investigation. Offered Every Term.

Restriction(s): Enrollment is limited to Graduate level students.

Repeatable for 998.99 Credits

BIO 8000 Special Topics Cr. 1-6

Various frontier aspects of biology. Work may include lectures, laboratories or discussion. Topics to be announced in Schedule of Classes. Offered Yearly.

Restriction(s): Enrollment is limited to Graduate level students.

Repeatable for 6 Credits

BIO 8995 Graduate Seminar in Biology Cr. 2

Presentations by graduate staff, advanced students, visiting lecturers. Offered Yearly.

Restriction(s): Enrollment is limited to students with a major in Biological Sciences; enrollment is limited to Graduate level students; enrollment limited to students in a Doctor of Philosophy or Master of Science degrees.

Repeatable for 4 Credits

BIO 8996 Research in Molecular Biotechnology Cr. 1-4

Students spend two semesters doing research under the guidance of faculty associated with the Molecular Biotechnology Program and in other laboratories. Offered Winter, Spring/Summer.

Restriction(s): Enrollment is limited to Graduate level students.

Repeatable for 8 Credits

BIO 8999 Master's Thesis Research and Direction Cr. 1-8

Offered Every Term.

Restriction(s): Enrollment limited to students with a class of Candidate Masters; enrollment is limited to Graduate level students.

Repeatable for 8 Credits

BIO 9990 Pre-Doctoral Candidacy Research Cr. 1-8

Research in preparation for doctoral dissertation. Offered Every Term.

Restriction(s): Enrollment is limited to Graduate level students.

Repeatable for 12 Credits

BIO 9991 Doctoral Candidate Status I: Dissertation Research and Direction Cr. 7.5

Offered Every Term.

Restriction(s): Enrollment is limited to Graduate level students.

BIO 9992 Doctoral Candidate Status II: Dissertation Research and Direction Cr. 7.5

Offered Every Term.

Prerequisite: BIO 9991 with a minimum grade of S

Restriction(s): Enrollment is limited to Graduate level students.

BIO 9993 Doctoral Candidate Status III: Dissertation Research and Direction Cr. 7.5

Offered Every Term.

Prerequisite: BIO 9992 with a minimum grade of S

Restriction(s): Enrollment is limited to Graduate level students.

BIO 9994 Doctoral Candidate Status IV: Dissertation Research and Direction Cr. 7.5

Offered Every Term.

Prerequisite: BIO 9993 with a minimum grade of S

Restriction(s): Enrollment is limited to Graduate level students.

BIO 9995 Candidate Maintenance Status: Doctoral Dissertation Research and Direction Cr. 0

Offered Every Term.

Restriction(s): Enrollment is limited to Graduate level students.

Course Material Fees: $370.26

Repeatable for 0 Credits

BIO 9996 Lab Rotation Cr. 2

Research training in faculty laboratories on a rotating basis, up to two labs per semester. Offered Every Term.

Restriction(s): Enrollment is limited to Graduate level students.

Repeatable for 4 Credits